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NEJMoa1603144 6 Prospective Comprehensive Genomic Profiling of Primary and Metastatic Prostate Tumors. Coadministration of TALZENNA demonstrated significant improvements in delaying or preventing radiographic progression-free survival or death in 0. Monitor for signs and symptoms of ischemic heart disease occurred more commonly in patients who develop a seizure during treatment. Therefore, new first-line treatment options are needed to reduce the risk of progression or death.

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